Hybrid selection for sequencing pathogen genomes from clinical samples
نویسندگان
چکیده
منابع مشابه
A cloud-compatible bioinformatics pipeline for ultrarapid pathogen identification from next-generation sequencing of clinical samples.
Unbiased next-generation sequencing (NGS) approaches enable comprehensive pathogen detection in the clinical microbiology laboratory and have numerous applications for public health surveillance, outbreak investigation, and the diagnosis of infectious diseases. However, practical deployment of the technology is hindered by the bioinformatics challenge of analyzing results accurately and in a cl...
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Next generation sequencing (NGS) has become a powerful approach in the field of infectious diseases and has revolutionized clinical microbiology and virology. However, despite the advances in these technologies, the use of NGS remains challenging for complex samples, such as ultra-low copy samples, samples with poor integrity of nucleic acids, and single cells. NGS is currently being adapted to...
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ژورنال
عنوان ژورنال: Genome Biology
سال: 2011
ISSN: 1465-6906
DOI: 10.1186/gb-2011-12-8-r73